LINC00665 and osteoarthritis: To further explore the regulatory function of LINC00665 in osteoarthritis, pcDNA3.1-LINC00665 was transfected into BMSCs to construct LINC00665 overexpression, and the transfection efficiency is shown in Fig. 2C. Cell viability analysis showed that pcDNA3.1-LINC00665 inhibited the proliferation level of BMSCs (Fig. 2D) and promoted the apoptosis of BMSCs (Fig. 2E).