This sub-network included hsa_circ_0001955, hsa_circ_0071681, hsa-miR-29a-3p, hsa-miR-150-5p, KLF4, MYC, CCNA2, RACGAP1, and CD44, provides a focused and meaningful representation of the selected genes and their interactions in CRC. This evidence concerns the gene CD44 and colorectal carcinoma.