Recent research suggests that the lncRNAs; taurine-upregulated gene 1 (TUG1) and metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) may play regulatory roles in the etiology of obesity-related illnesses and the control of lipid metabolism25. The gene discussed is MALAT1; the disease is obesity due to melanocortin 4 receptor deficiency.