After external validating the upregulation of MELK, FZD2, IL1RN, NOVA1, TMEM97, PTPRZ1, and PDGFC in GBM tissues compared to non-tumoral samples, we applied single-cell RNA sequencing analyses to identify which cell types are responsible for the increased expression of these genes. The gene discussed is PTPRZ1; the disease is glioblastoma.