As a result, tandem CAR T cells can recognize different antigens expressed in a single cancer cell (e.g., human epidermal growth factor receptor 2 (Her2) and interleukin 13 receptor alpha 2 (IL13Rα2),80 CD19 and CD2081), and therefore reduce the possibility of tumor escape.82,83. This evidence concerns the gene ERBB2 and neoplasm.