This hair phenotype depended on RIPK1 kinase activity as Ikke-/-Tbk1-/-Ripk1D138N/D138N and IkkeK38A/K38ATbk1D135N/D135NRipk1D138N/D138N did not show transient alopecia (Fig. 1f, g). This evidence concerns the gene IKBKE and alopecia.