Additionally, bulk RNA analysis revealed significant increases in NTSR1, BCL6, ZDHHC19, MGLL, and ALPK1 in sepsis, and significant decreases in VAV2 and SATB1 in sepsis; FCHO1 showed a significant decrease in sepsis patients who did not survive compared to those who survived at 28 days. Here, ALPK1 is linked to Sepsis.