APP and Sepsis: For other infectious diseases, we found that FMN1 had lower expression in Pre-B cells (CD34−) and Monocytes of healthy individuals compared to sepsis patients, MGLL had lower expression in Platelets of healthy individuals compared to sepsis patients, and APP and CE NPN had lower expression in Pre-B cells (CD34−) of healthy individuals compared to sepsis patients (Additional file 16: Figure S9, Additional file 17: Figure S10, Additional file 18: Figure S11).