They obtained the MV-attenuated Edmonton MV (MV-EDM) vaccine strain through further continuous passage, which can preferentially infect and dissolve various cancer cells and express human carcinoembryonic antigen (MV-CEA) or human sodium iodide transporter (MV-NIS) by genetic engineering to obtain a virus strain with more substantial oncolytic effects [39]. The gene discussed is CEACAM5; the disease is cancer.