HMOX1 and neuroblastoma: DHPA, an antioxidant and anti-inflammatory substance, inhibited Aβ1-42/Cu2+/ascorbic acid-induced oxidative damages by regulating mitochondrial apoptosis in human neuroblastoma SH-SY5Y cells, inducing the KEAP1/Nrf2/HO-1 signaling axis and enhancing the expression of NQO1 [123].