HDGFL2 and malaria: In Uganda, there are recent reports of emerging malaria parasites that evade detection by the routinely used malaria HRP2-based RDTs due to pfhrp2 gene deletions [5–7] and those that evade treatment due to reduced sensitivity to artemisinin-based combination therapy (ACT) mediated by genetic mutations in the parasite’s kelch13 propeller gene [8–11].