We evaluated VEGF (min: 23.68 pg/ml; Me: 244.04 pg/ml; max: 2158.91 pg/ml) and bFGF (min: 4171.56 pg/ml; Me: 6809.27 pg/ml; max: 18,011.25 pg/ml) blood serum levels in children with JIA. This evidence concerns the gene FGF2 and juvenile idiopathic arthritis.