VEGFA and juvenile idiopathic arthritis: Additionally, a significantly higher mean VEGF level was observed in patients with JIA onset at older than 15 years than in children with JIA onset at 3 to 5 years of age (p = 0.010), at 6 to 10 years of age (p = 0.022), and at 11 to 14 years of age (p = 0.034).