SiRNA targeting CCNB2 (si CCNB2 1# and si CCNB2 2#) was transfected into NPC cells to inhibit the intracellular CCNB2 activity, and RT-qPCR showed a substantial decrease in CCNB2 expression after transfection. This evidence concerns the gene CCNB2 and nasopharyngeal carcinoma.