The findings showed a strong correlation between CD274 expression and immune subtype including C1-C6 of PRAD, SKCM, UVM, SARC, MESO, LIHC, BLCA, OV, LUAD, BRCA, LGG, CECS, UCS, COAD, HNSC, LUSC, PCPG (pheochromocytoma and paraganglioma), STAD, READ, UCEC, and TGCT (uveal melanoma) (Supplementary Fig. S5). This evidence concerns the gene CD274 and hereditary pheochromocytoma-paraganglioma.