Apart from the same data of 11 types of cancers presented by TCGA above, we also found that CD274 was highly expressed in COAD, BRCA, DLBC (lymphoid neoplasm diffuse large B cell lymphoma), THCA (thyroid carcinoma), KIRP, LCG, CESC (cervical squamous cell carcinoma), TGCT (testicular germ cell tumors), PAAD, SKCM (skin cutaneous melanoma), and READ (rectum adenocarcinoma), downregulated in tumors relative to normal tissues in OV (ovarian serous cystadenocarcinoma), ACC (adrenocortical carcinoma), and UCS (uterine carcinosarcoma). This evidence concerns the gene CD274 and rectum adenocarcinoma.