METTL3 and liver cancer: Therefore, this article comprehensively reviews the currently popular m6A regulatory factors, analyzes their main roles in the occurrence and development of liver cancer, and reveals the expression changes of related regulatory factors, such as the significant upregulation of METTL3 expression, which is related to the poor prognosis of liver cancer, in order to provide new methods and pathways for the diagnosis and prognosis of liver cancer.