AKT1 and posterior cortical atrophy: A study on the metabolic effects of METTL3 on long-stranded non-coding RNAs found that METTL3-mediated m6A-modified lncRNA MALAT1 promoted PCa proliferation by activating the PI3K/AKT signaling pathway and that METTL3-mediated lncRNA PVT1 could regulate the miR-27b-3b/BLM signaling pathway [122, 123].