Furthermore, multivariate analysis showed that CBI was an independent factor associated with the severity of hepatic necroinflammation after adjusting for age, gender, BMI z-score, CBI, globulin, ALT, aspartate aminotransferase (AST), albumin, TC, TG, HDL-C, LDL-C, the stage of fibrosis and the degree of steatosis in NAFLD children (OR 6.125, 95%CI 1.958–19.158). The gene discussed is ALB; the disease is steatosis.