These HCW + IGRAS(LTBI), previous TB patients and HC were further amalgamated into non-ATB patients, The ROC curves were generated by the levels of cytokines stimulated with antigens in TB1 (Fig. 6A) and TB2 (Fig. 6B) tubes separately subtracted with the corresponding cytokine levels in the Nil tube and in TB2 tube minus TB1 tube (Fig. 6C). Here, REEP5 is linked to tuberculosis.