Notably, this case had high expression of CD30 (normalized count = 8471.48, mean = 358.98, standard deviation = 1622.66), a feature of anaplastic large cell lymphoma [40], which may have accounted for its clustering away from the typical canine CD4+ PTCL cases. This evidence concerns the gene TNFRSF8 and mature T-cell and NK-cell non-Hodgkin lymphoma.