Then, univariate Cox regression analysis selected 9 prognostic OS-associated genes (STK25, CTNNB1, HSPB1, MMP3, SFPQ, RNF112, NOL3, PAGE4, NCOA7) in CRC based on the relation between genes and overall survival of CRC patients in TCGA database (Fig. 2A). Here, RNF112 is linked to colorectal carcinoma.