SLC22A12 and hypouricemia, renal, 2: Currently, only two urate transporters related to the Mendelian disorders have been reported: SLC22A12 (OMIM 220150), which is responsible for renal hypouricemia type 1 (RHUC1) [41], and SLC2A9 (OMIM612076) which is responsible for renal hypouricemia type 2 (RHUC2) [42, 43].