However, markers in the hedgehog signalling pathway such as PTCH1/2, HHIP, EPCAM, a diagnostic marker for BCC (42), and IGKC, a immunologic marker of solid cancer (43), were highly expressed in BCC basal keratinocytes compared to healthy (SI Appendix, Fig. S8D). Here, EPCAM is linked to skin basal cell carcinoma.