Various types of vaccines against PCSK9 are currently being tested: peptide vaccines (epitope vaccines), nanoliposome vaccines containing the PCSK9 epitope conjugated to the Tetanus epitope, virus-like particle (VLP)-peptide vaccines anti-PCSK9, etc. The main differences include the carrier used (nanoliposomes, VLPs), the presence of an adjuvant (tetanus), valenty, and the length of the antigen PCSK9 [49]. The gene discussed is PCSK9; the disease is tetanus.