Table 2 summarizes key models. Among them, GEMMs resembling ovarian serous carcinomas developed by using recombinant Ad-Cre in MOSECs include Apc–/–Pten–/– (53), Trp53–/–Rb–/– (24, 55), Trp53–/–Brca1–/–Myc–/– (56), Pten–/–Pik3ca(H1047R) (57), and Trp53–/–Brca1–/–Rb–/– (58). GEMMs for other OC subtypes developed using Ad-Cre include ovarian clear cell carcinoma Arid1a–/–Pik3ca(H1047R) (59), ovarian endometrioid cancer Arid1a–/–Pten–/–Apc–/– (60), and Arid1a–/–Pten–/– (61). This evidence concerns the gene PIK3CA and ovarian endometrioid adenocarcinoma.