All three macaques (C-1, C-2, C-3) showed disease features including anorexia, lethargy, central nervous system anomalies, leukopoenia, thrombocytopenia, hypoalbuminemia, and elevations in circulating levels of liver-associated enzymes and C-reactive protein consistent with previous LF studies [3,22,25,26] (Supplementary Table 1). The gene discussed is CRP; the disease is Thrombocytopenia.