HIF1A and Right ventricular hypertrophy: A study shows63 that hypoxia induced PAAF is accompanied by a sharp decline in miR-29a-3p; after HIF-1α is knocked out, the increase in miR-29a-3p of adventitial cells of posterior vessels promotes the proliferation and migration of PAAF and the expression of α-SMA and extracellular matrix protein, significantly reduces pulmonary artery pressure, right ventricular hypertrophy index, and improves pulmonary vascular remodeling.