In order to continue to study the biological characteristics of these genes, we analyzed the enrichment pathways of these genes in KEGG based on GSEA, and obtained Glycosaminoglycan biosynthesis chondroitin sulfate, Viral myocarditis, Taste transduction, RNA polymerase, Toll-like receptor signaling pathway, Beta alanine metabolism, Melanoma, etc. Among them, the Toll-like receptor signaling pathway enriched by IL1A gene is an inflammation-related pathway, which has been confirmed to be involved in the pathogenesis of gout38. Here, IL1A is linked to melanoma.