IL1A and melanoma: These 11 gene-enriched pathways included glycosaminoglycan biosynthesis chondroitin sulfate, vasopressin regulated water reabsorption, viral myocarditis, taste transduction, RNA polymerase,Toll-like receptor signaling pathway, beta alanine metabolism, inositol phosphate metabolism, MTOR signaling pathway, melanoma, etc. Among them, the Toll-like receptor signaling pathway enriched by IL1A is an inflammatory pathway, which is related to gout, so we targeted IL1A for subsequent analysis.