These 11 gene-enriched pathways included glycosaminoglycan biosynthesis chondroitin sulfate, vasopressin regulated water reabsorption, viral myocarditis, taste transduction, RNA polymerase,Toll-like receptor signaling pathway, beta alanine metabolism, inositol phosphate metabolism, MTOR signaling pathway, melanoma, etc. Among them, the Toll-like receptor signaling pathway enriched by IL1A is an inflammatory pathway, which is related to gout, so we targeted IL1A for subsequent analysis. This evidence concerns the gene IL1A and gout.