NOTCH3 and breast carcinoma: Consistently, for breast cancer patients, higher expression of NOTCH3 was positively correlated with metastasis-free survival (MFS) (p = 0.0011, HR = 0.519) (Figure 6E), whereas the expression level of ZEB1 was negatively correlated with MFS (p = 0.00413, HR = 2.43) (Figure 6F).