The TIMER analysis revealed that SARDH expression was positively related with tumor purity (correlation =0.233) and negatively correlated with CD8+ T cells (r=-0.098), neutrophils (r =-0.176), Neutrophil (r =-0.176), CD4+ T cells (r =-0.267), dendritic cells (r=-0.229), B cells (r =-0.170), as well as macrophages (r =-0.304) (Figure 8A). Here, CD4 is linked to neoplasm.