Conversely, RIPK4 displays heightened expression levels in most cancers, except for GBM, breast cancer (BRCA), liver hepatocellular carcinoma (LIHC), skin cutaneous melanoma (SKCM), ACC, and KICH, where it exhibits decreased expression levels relative to normal tissues (Figure 3D). The gene discussed is RIPK4; the disease is invasive breast carcinoma.