We utilized RNA-seq data from TCGA and GTEX database to analyze the expression of IGFBP5 between various tumors and normal tissues, and the results showed the IGFBP5 expression in Lymphoid Neoplasm Diffuse Large B-cell Lymphoma (DLBC), glioblastoma multiforme (GBM), brain lower grade glioma (LGG), lung squamous cell carcinoma (LUSC), pancreatic adenocarcinoma (PAAD), and thymoma (THYM) was higher than that in normal tissues (Figure 1A). This evidence concerns the gene IGFBP5 and lymphoid neoplasm.