In another study, researchers reported that the tumour-to-contralateral breast, tumour-to-liver, tumour-to-lung and tumour-to-mediastinum SUVmax ratios were correlated with histologic type, tumour size, histologic grade, pleomorphism, mitotic count, lymphatic invasion, tumour necrosis, ER expression, Ki-67 index, ALN metastases, menopause and triple negativity (12). Here, ESR1 is linked to neoplasm.