In addition, we also found that the expression of SECTM1 in GBM cell lines was consistent with clinical tissue samples, and qPCR results showed that compared with human astrocytes (HA), the expression level of SECTM1 mRNA in human GBM cell lines (U87 MG, U251 MG, LN229, KNS81) was significantly increased (Figure S2A). Here, SECTM1 is linked to glioblastoma.