SECTM1 and neoplasm: To further investigate the effects of SECTM1 knockdown on the tumorigenicity of U87 MG cells and on tumor growth and invasion, we used U87 MG-LUC cells (U87 MG-LUC-NC, U87 MG- LUC-sh1, U87 MG- LUC-sh2) to in situ tumorigenicity in nude mice and, at different time points (5 days, 10 days, 15 days) detected the luminescence range and intensity of the tumors in the mouse brain.