In addition, YAP signaling in cancer cells can facilitate recruitment of macrophages or myeloid-derived suppressor cells (MDSC) to the tumor microenvironment by regulating CXCL5, IL-6 and Csf1-3, and inhibition of YAP-mediated immune cell infiltration impairs tumor growth 117, 118. Here, YAP1 is linked to neoplasm.