In a patient with PD-L1-positive primary lung cancer and multiple bone metastases (TPS = 40%) and at a lower radioactive dose than [18F]FDG PET/CT (540.2 MBq, 1 h), [89Zr]Zr-DFO-KN035 immunoPET (85.1 MBq, 54 h) demonstrated sensitive tumor-specific imaging and revealed numerous metastatic lesions, such as multiple bone metastases (Figure 1B). The gene discussed is CD274; the disease is lung cancer.