In patients with PD-L1-positive lung cancer, as shown by the different cross-sectional images in Figure 3A, [89Zr]Zr-DFO-KN035 immunoPET can detect numerous metastatic lesions, such as bone, LN, and adrenal metastases, and [89Zr]Zr-DFO-KN035 had uptakes and high TBRs at numerous tumor sites. The gene discussed is CD274; the disease is neoplasm.