In gastric cancer, Fujii et al. examined endosialin expression in a tissue microarray that contained 945 tumor tissues and found that endosialin was specifically expressed in CAFs, and its expression was significantly correlated with recurrence-free survival, overall survival, cancer-related overall survival, scirrhous subtype, tumor depth, nodal status, distant metastasis, serosal invasion, lymphatic or venous vessel infiltration and pTMN stage 25. The gene discussed is CD248; the disease is gastric cancer.