Injection of complex of IL-2 and anti-IL-2 monoclonal antibody into (NZB×NZW)F1 mice may lead to expansion of CD4+CD25+Foxp3+ Tregs in kidneys and spleen, along with reduced renal infiltration of T cells, B cells, reduced proteinuria, improved glomerular and tubular injury, vasculitis scores, and less renal deposition of IgG and C3 (160). The gene discussed is IL2; the disease is vasculitis.