The expression of IFNγ response gene IP-10 was elevated in SLE patients’ monocytes, and stimulation of SLE PBMCs with IFNγ significantly induced STAT1 phosphorylation, suggesting that IFNγ may be involved in SLE pathogenesis via regulating STAT1 signaling (131). This evidence concerns the gene STAT1 and systemic lupus erythematosus.