Moreover, serum levels of TGF-β1 in Spanish SLE patients treated with prednisone, hydroxychloroquine, methotrexate, mycophenolate mofetil, azathioprine, rituximab, and belimumab were related to high levels of LDL/HDL ratio, Katz severity index, atherogenic index, carotid plaque, and ocular and cardiovascular manifestations (105, 106). The gene discussed is TGFB1; the disease is systemic lupus erythematosus.