The common mutated genes in der(1;7) patients and their frequencies were as follows: RUNX1 (40.8%, 95% CI 32.8% to 48.7%), ETNK1 (28.1%, 95% CI 19.8% to 36.3%), EZH2 (24.8%, 95% CI 17.3% to 32.3%), GATA2 (11% in adult but 72.7% in pediatric MDS). The gene discussed is RUNX1; the disease is myelodysplastic syndrome.