The aim of the study is to explore the role and mechanism of methyltransferase-like 3 (METTL3) mediated up-regulation of N6-methyladenosine (m6A) modified lncRNA THAP7-AS1 expression in promoting the development of lung cancer.<h4>Methods</h4>Samples of 120 lung cancer and corresponding paracancerous tissues were collected. Here, THAP7 is linked to lung cancer.