TLL1 and hepatocellular carcinoma: Another immune-related SNP identified in a Japanese population linked to HCC development in the setting of HCV infection is SNP rs17047200 (OR, 2.37; 95% CI, 1.74–3.23) at the TLL1 gene locus, which was significantly associated with the development of HCC after the eradication of HCV and achievement of sustained virologic response through interferon-based therapy.73