A recent study reported that it could convert androgen precursors into active androgens to promote the development of prostate cancer (Henke et al., 2019), and Ruminococcus could also promote the progression of prostate cancer by upregulating the expression of LPCAT1 and DNA repair proteins in prostate tissues (Liu et al., 2021). The gene discussed is LPCAT1; the disease is prostate carcinoma.