These mice exhibited increased expression of several genes of the CXC chemokine gene cluster, including CXCL1, CXCL2, CXCL3, and Pf4, and classic proinflammatory cytokine genes such as IL-1ß and IL-6, which contribute to atherosclerosis (24). The gene discussed is CXCL2; the disease is atherosclerosis.