Associations exist between CHIP and several types of cancer, including bladder tumors (38, 140, 141), breast cancer (38, 140–143), colorectal cancer (38, 140, 142, 144, 145), endometrial cancer (38, 140), esophagogastric cancer (38, 140, 143), head and neck cancer (38, 140, 143), kidney cancer (38, 140, 141), lung cancer (38, 140–143), melanoma (38, 140, 141), ovarian cancer (38, 41, 140, 143), pancreatic cancer (38, 140–143), prostate cancer (38, 140–142, 146), and thyroid cancer (38, 140, 141, 143). This evidence concerns the gene STUB1 and breast cancer.