REN and type 2 diabetes mellitus: The proteins encoded by 2707 differentially upregulated genes (≥1.0) in the edible seed samples carry biopeptides associated with 18 different types of roles in alleviating many diseases, including type-2 diabetes (DPP-4), high blood pressure (ACE inhibitors, Renin inhibitor), antiaging, antiviral, immunomodulating, etc. (Supplementary File 1).