Hepatic or Renal disease, Ethanol abuse, Malignancy, Older (age >75 years), Reduced platelet count or function, Rebleeding risk, Hypertension (uncontrolled), Anemia, Genetic factors (CYP2C9 single nucleotide polymorphisms), Excessive fall risk (including neuropsychiatric disease), and Stroke. Here, CYP2C9 is linked to Stroke.