Hepatic or Renal disease, Ethanol abuse, Malignancy, Older (age >75 years), Reduced platelet count or function, Rebleeding risk, Hypertension (uncontrolled), Anemia, Genetic factors (CYP2C9 single nucleotide polymorphisms), Excessive fall risk (including neuropsychiatric disease), and Stroke. Here, CYP2C9 is linked to kidney disorder.