VEGFA and Alzheimer disease: Such a chemotactic response of microglia to VEGF may play a key role in the regulation of Aβ phagocytosis, because we and others have previously shown that VEGF accumulates in and around Aβ plaques in the brain of AD patients (Yang et al., 2004; Ryu et al., 2009; Thomas et al., 2015; Martin et al., 2021).