As the response of microglial cells to brain Aβf deposition in plaque is a hallmark of AD, we next used an ex vivo plaque clearance assay (Bard et al., 2000; Xiang et al., 2016; Colombo et al., 2021) to further investigate VEGF impact on microglia Aβf phagocytosis. Here, VEGFA is linked to Alzheimer disease.