FTO and obesity due to melanocortin 4 receptor deficiency: The FTO rs9939609 polymorphism was independently associated with dyslipidemia after adusting for age, sex and smoking (P = 0.05), but the model lost its significance when the variables including obesity, dyslipidemia, hyperhomocysteinemia, hyperuricemia, hypertension and CAD were included (P = 0.12).