HCRT and depressive disorder: Studies have shown that acupuncture points such as HT7, SP6, and GV20 can regulate neurotransmitters such as 5-hydroxytryptamine, norepinephrine, dopamine, γ-aminobutyric acid, glutamate, acetylcholine, and orexin, to adjust the structure of sleep and improve the state of anxiety and depression (45–47).