F, female; M, male; SC, subcutaneous; ACQ-5, Asthma Control Questionnaire, five-item version; OCS, oral corticosteroid; FEV1, forced expiratory volume in the first second; IV, intravenous; ACT, asthma control test; IL-5, interleukin-5; PK, pharmacokinetics; PD, pharmacodynamics; RCT, randomized controlled trial; QoL, quality of life; FeNO, fractional exhaled nitric oxide; FEF, forced expiratory flow. This evidence concerns the gene IL5 and asthma.