WWOX and autosomal recessive spinocerebellar ataxia 12: Interestingly, the WWOX protein is mostly expressed in the cerebellar cortex and in specific cell types, such as basket cells and granule cells, and hypomorphic mutations of WWOX have been associated with cerebellar disorders such as Spinocerebellar Ataxia Type 12 (SCAR12) (MIM: 614322).