WDR35 and cranioectodermal dysplasia: Our preliminary results showed that hURECs from the CED patient present with a different cilium morphology variation as compared to controls, most likely due to the identified variants in WDR35. Analysis of the CED patient-derived URECs revealed a significant increase in cilium length, width, and volume compared to controls (based on data using Acet-Tub, ARL13B, and PCNT to visualize the cilium parameters).