It was shown that the absolute number of mtDNA copies of CD14+ monocytes was significantly higher in the group of patients with SSc, 108 [60–162] compared to the control group, 72 [59–79], p = 0.011*, while the absolute number of mtDNA copies of all cell populations circulating in the blood was decreased in SSc patients, 109 [72–171] than in control individuals, 128 [85–227], but the difference between groups was not significant, p = 0.171. Here, CD14 is linked to systemic sclerosis.